NDRG4 antibody

Catalog No. ABIN317933

The Rabbit Polyclonal anti-NDRG4 antibody is suitable to detect NDRG4 in samples from Human, Mouse and Rat. It has been validated for WB and IHC (p).

Quick Overview for NDRG4 antibody (ABIN317933)

Target: NDRG4 (NDRG Family Member 4 (NDRG4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDRG4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-NDRG4 Antibody

Specificity: NDRG4 antibody detects endogenous levels of NDRG4 protein. (region surrounding Gly217)

Purification: Affinity chromatography

Application Details

Application Notes: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for NDRG4

Target: NDRG4 (NDRG Family Member 4 (NDRG4))

Alternative Name: NDRG4

Background: The N-Myc downstream regulated gene (NDRG) family is comprised of four members, namely NDRG1, NDRG2, NDRG3 and NDRG4, all of which share 57-65 % homology. NDRG4 (NDRG family member 4), also known as SMAP8 (smooth muscle-associated protein 8) or BDM1 (brain development-related molecule 1), is a 352 amino acid cytoplasmic protein that belongs to the NDRG family. Expressed specifically in brain and heart, NDRG4 is thought to function as a regulator of mitogenic signaling in vascular smooth muscle cells. Additionally, NDRG4 may play a role in early postnatal development and may mediate the differentiation and subsequent function of neuronal cells. NDRG4 is expressed as six isoforms (the first three of which are designated NDRG4- BVar, NDRG4-B and NDRG4-H) due to alternative splicing events.Synonyms: BDM1, Brain development-related molecule 1, KIAA1180

Molecular Weight: approx. 34 kDa

Gene ID: 65009

NCBI Accession: NP_001123959

UniProt: Q9ULP0