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Antibodies
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anti-Hepatitis A Virus Cellular Receptor 1 (HAVCR1) antibody
Hepatitis A Virus Cellular Receptor 1 (HAVCR1) antibody
| Antigen |
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| Synonyms |
KIM1, TIM1, HAVCR, KIM-1, TIM-1, TIMD1, HAVCR-1, Kim1, HAVCR1, LOC100226241 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN318766 |
| Quantity |
50 µg (1.0mg/ml) (Variants) |
| Price |
270.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: TIMD-1, TIM1, TIM-1, T cell membrane protein 1, HAVCR-1, T cell immunoglobulin and mucindomain-containing protein 1, Hepatitis A virus cellular receptor 1
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Alternative name
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TIMD1 / HAVCR1
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Swiss-Prot
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Q96D42
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Immunogen
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16 amino acid peptide sequence near the centre of human TIM-1.
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Cross-Reactivity
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Human, Mouse (Murine), Rat (Rattus)
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Isotype
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IgG (Matching secondary antibodies)
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Description
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TIM-1 is a key cell surface protein that binds TIM-4, leading to T cell proliferation and Thelper type 2 (Th2) cytokine production. TIM-1 has also been shown to bind and activatemacrophages. Two splice variants for human TIM-1 exist, TIM-1a is predominantly expressed in the liver,whilst TIM-1b is expressed in the kidney. Expression of TIM-1 in the kidney is thought to beupregulated in damaged tissue, and is thought to assist healing. TIM-1 polymorphisms are associated with asthma.
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Specificity
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This antibody detects T cell immunoglobulin mucin-1 (TIM-1), which was first identified asthe receptor used by hepatitis A for viral entry (it is also known as the hepatitis A viruscellular receptor- HAVCR). Species: Human, Mouse, Rat. Others not tested.
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Application Notes
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Western Blot: 1.0 - 2.0g/ml, detects a band of approximately 49kDa in human uterustissue lysate. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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1.0mg/ml
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Purification
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Purified
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Buffer
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Phosphate buffered saline containing 0.02% Sodium Azide
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Storage
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.
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Restrictions
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For Research Use only
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Alternatives for antigen "Hepatitis A Virus Cellular Receptor 1 (HAVCR1)", type "Antibodies"
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