IL-6 Receptor antibody (Extracellular Domain)

Catalog No. ABIN327366

Product Details anti-IL-6 Receptor Antibody

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Binding Specificity: AA 20-357, Extracellular Domain

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-6 Receptor antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunocytochemistry (ICC)

Specificity: Recognizes mouse IL-6R. Does not crossreact with rhIL-6R.

Purification: Protein G purified

Immunogen: Recombinant protein corresponding to aa20-357 from mouse IL-6R expressed in NSO cells (P22272).

Type of Immunogen: Recombinant protein

Isotype: IgG2a

Application Details

Application Notes: Approved: Flo, ICC

Usage: Suitable for use in Flow Cytometry and Immunocytochemistry. Flow Cytometry: 2.5 μg/10e6 cells using mouse CD3+ splenocytes. Immunocytochemistry: 8-25 μg/mL using immersion fixed mouse splenocytes.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 1 mL sterile PBS

Concentration: Lot specific

Buffer: Lyophilized from PBS,  pH 7.4, 5 % trehalose

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for IL-6 Receptor

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Alternative Name: IL6R / IL6 Receptor (IL6R Products)

Background: Name/Gene ID: IL6R
Family: Interleukin

Synonyms: IL6R, CD126, gp80, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL6Q, IL-6 receptor subunit alpha, IL-6R 1, IL-6R-1, Interleukin 6 receptor, Membrane glycoprotein 80, CD126 antigen, IL6RA, IL6RQ

Gene ID: 3570

UniProt: P08887

Pathways: JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints