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Desmin (DES) antibody
| Antigen | Desmin (DES) |
| Synonyms |
DES, des-a, MGC52614, des-b, MGC80853, CSM1, CSM2, CMD1I, FLJ12025, FLJ39719, FLJ41013, FLJ41793, des, csm1, csm2, desm, cmd1i, MGC75911, LOC395906, LOC100220724, desmin, cb290, fb59a12, MGC109859, wu ...
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| Clonality | Polyclonal |
| Host |
 Alternatives Goat |
| Reactivity |
Alternatives Human |
| Application |
Alternatives ELISA, Western Blotting (WB)
|
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1 reference available |
| Catalog no. | ABIN334386 |
| Quantity | 100 ug |
| Price | 501.80 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 5 Business Days |
Additional Information
| Alternative name | Desmin |
| Gene ID | 1674, 13346 (mouse), 64362 (rat) |
| Immunogen | C-RDGEVVSEATQQQHE |
| Description | All names and symbols: DES, desmin, CMD1I, CSM1, CSM2, FLJ12025, FLJ39719, FLJ41013, FLJ41793, intermediate filament protein. Official Symbol: DES. RefSeq number(s): NP_001918.3 |
| Specificity | Human, Mouse, Rat, Dog, Cow |
| Synonyms | DES, des-a, MGC52614, des-b, MGC80853, CSM1, CSM2, CMD1I, FLJ12025, FLJ39719, FLJ41013, FLJ41793, des, csm1, csm2, desm, cmd1i, MGC75911, LOC395906, LOC100220724, desmin, cb290, fb59a12, MGC109859, wu:fb59a12, zgc:109859, MGC154009, wu:fc11d08 |
Application Details
| Application Notes | Peptide ELISA: antibody detection limit dilution 1:2,000. Western Blot: Approx. 55kDa band observed in Human Skeletal Muscle lysates (calculated MW of 53.5kDa according to NP_001918.3). Recommended concentration: 0.1-0.3µg/ml. |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Storage | Aliquot and store at -20°C. Minimize freezing and thawing. |
| Research Area | Cancer, Cytoskeleton |
| Restrictions | For Research Use only |
Images
| ABIN334386 (0.2µg/ml) staining of Human Skeletal Muscle lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. |
Publications
| Publications |
Chen, Chang, Trivedi et al.: "Caspase proteolysis of desmin produces a dominant-negative inhibitor of intermediate filaments and promotes apoptosis." in: The Journal of biological chemistry, Vol. 278, Issue 9, pp. 6848-53, 2003 (PubMed).
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Alternatives
Alternatives for antigen "Desmin (DES)", type "Antibodies"
| Hosts | Rabbit (39), Mouse (30), Goat (3) |
| Reactivities | Human (54), Rat (Rattus) (22), Mouse (Murine) (15), Chicken (8), Dog (Canine) (7), Hamster (7), Cow (Bovine) (3), Cat (Feline) (2), Mammalian (2), Monkey (2), Pig (Porcine) (2), Rabbit (2) |
| Applications | Western Blotting (WB) (50), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (34), Immunohistochemistry (IHC) (26), Immunohistochemistry (Frozen Sections) (IHC (fro)) (22), Enzyme Immunoassay (EIA) (12), Immunoprecipitation (IP) (9), ELISA (7), Immunofluorescence (IF) (6), Dot Blot (Dot) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (1) |
| Epitopes | C-Term (4), pThr16 (2), Ab-60 (1), pSer60 (1), ppT16 (1) |
