RPGRIP1-Like (RPGRIP1L) antibody

Antigen: RPGRIP1-Like (RPGRIP1L)

Synonyms: MKS5, CORS3, JBTS7, NPHP8, KIAA1005, DKFZp686C0668, Ftm, 4931437C01, 1700047E16Rik, RGD1311099, si:ch1073-301i20.1, mks5, cors3, jbts7, nphp8

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN334483

Additional Information

Alternative name: RPGRIP1L

Gene ID: 23322

Immunogen: C-DKENNKAKRDILK

Description: All names and symbols: RPGRIP1-like , CORS3 , DKFZp686C0668 , JBTS7 , KIAA1005 , MKS5. Official Symbol: RPGRIP1L. RefSeq number(s): NP_056087.2

Specificity: Human, Dog,

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:64,000. Western Blot: Approx 150kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 151kDa according to NP_056087.2). Recommended concentration: 0.3-1µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Research Area: Neurology, Neurogenesis

Restrictions: For Research Use only

Images

ABIN334483 (0.3µg/ml) staining of Human Brain (Cerebellum) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Publications

Publications: Arts, Doherty, van Beersum et al.: "Mutations in the gene encoding the basal body protein RPGRIP1L, a nephrocystin-4 interactor, cause Joubert syndrome." in: Nature genetics, Vol. 39, Issue 7, pp. 882-8, 2007 (PubMed).