Asynaptic Phenotype Protein 1 (ASY1) antibody

Antigen: Asynaptic Phenotype Protein 1 (ASY1)

Clonality: Monoclonal

Host: Mouse

Reactivity: Wheat (Triticum)

Application: Western Blotting (WB), ELISA

Catalog no.: ABIN334570

Additional Information

Immunogen: KLH-conjugated synthetic pepitde chosen from Triticum aestivum ASY1 A7TVU8

Format: Lyophilized

Description: Pairing and synapsis of homologous chromosomes is required for normalchromosome segregation and the exchange of genetic material via recombinationduring meiosis. Synapsis is complete at pachytene following the formation of atri-partite proteinaceous structure known as the synaptonemal complex (SC). Inyeast, HOP1 is essential for formation of the SC, and localises along chromosomeaxes during prophase I. Homologues in Arabidopsis (AtASY1), Brassica(BoASY1) and rice (OsPAIR2) have been isolated through analysis of mutantsthat display decreased fertility due to severely reduced synapsis of homologouschromosomes. Analysis of these genes has indicated that they play a similar roleto HOP1 in pairing and formation of the SC through localisation to axial/lateralelements of the SC.

Specificity: Predicted reactivity: Triticum aestivum.

Application Details

Application Notes: Recommended Dilution 1: 1000 (WB), 1: 10 000 (ELISA).

Purity: Affinity purified

Storage: store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior toopening them to avoid any losses that might occur from lyophilized materialadhering to the cap or sides of the tubes.

Research Area: Plant/Algal Physiology

Restrictions: For Research Use only