DR3/LARD antibody (AA 25-40)

Catalog No. ABIN343911

The Rabbit Polyclonal anti-DR3/LARD antibody (ABIN343911) specifically detects DR3/LARD in WB, ELISA, IHC and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for DR3/LARD antibody (AA 25-40) (ABIN343911)

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DR3/LARD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DR3/LARD Antibody

Binding Specificity: AA 25-40

Specificity: DR3 has no cross reaction to other death receptors.

Purification: Ion exchange chromatography

Isotype: IgG

Application Details

Application Notes: Approved: ELISA, IHC, IHC-P (10 μg/mL), WB (1:500 - 1:1000)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles. Store undiluted.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 3 months and -20°C, stable for up to 1 year. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DR3/LARD

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Alternative Name: TNFRSF25 / DR3

Background: Name/Gene ID: TNFRSF25
Family: TNF Receptor

Synonyms: TNFRSF25, APO-3, APO3, DDR3, Death receptor 3, DR3, Death receptor beta, LARD, Protein WSL, TR3, WSL, WSL-1, WSL-LR, Apoptosis inducing receptor, TNFRSF12, WSL1, Protein WSL-1, TRAMP

Gene ID: 8718

UniProt: Q93038

Pathways: Apoptosis