Ganglioside-OacGD3 antibody

Antigen: Ganglioside-OacGD3

Clonality: Monoclonal (Cov7H2)

Host: Mouse

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN346820

Additional Information

Immunogen: Ganglioside-OacGD3

Format: Tissue culture supernatant

Isotype: IgG3 kappa  (Matching secondary antibodies)

Clone: Cov7H2

Specificity: Monoclonal antibody reacts specifically with OAcGD3 ganglioside : OAcNeuAc alpha 2-8NeuAc alpha 2-3Gal beta 1-4Glc beta 1-1Cer. Cross Reactivities: Not yet tested

Application Details

Application Notes: Optimal dilutions should be determined by the end user. The following are guidelines only: ELISA : 1/5 to 1/50. Western Blot : 1/5 to 1/20

Buffer: Lyophilized from 0,5 ml of tissue culture supernatant. Preservative: None.

Storage: Short term storage: +4°C. Long term storage: -20°C

Restrictions: For Research Use only

Publications

Publications: Zebda, Pedron, Rebbaa et al.: "Deficiency of ganglioside biosynthesis in metastatic human melanoma cells: relevance of CMP-NeuAc:LacCer alpha 2-3 sialyltransferase (GM3 synthase)." in: FEBS letters, Vol. 362, Issue 2, pp. 161-4, 1995 (PubMed).

Portoukalian, David, Gain et al.: "Shedding of GD2 ganglioside in patients with retinoblastoma." in: International journal of cancer. Journal international du cancer, Vol. 53, Issue 6, pp. 948-51, 1993 (PubMed).

Thomas, Buronfosse, Combaret et al.: "Gangliosides protect human melanoma cells from ionizing radiation-induced clonogenic cell death." in: Glycoconjugate journal, Vol. 13, Issue 3, pp. 377-84, 1997 (PubMed).

Cerato, Birkle, Portoukalian et al.: "Variable region gene segments of nine monoclonal antibodies specific to disialogangliosides (GD2, GD3) and their O-acetylated derivatives." in: Hybridoma, Vol. 16, Issue 4, pp. 307-16, 1997 (PubMed).