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Sortilin-Related VPS10 Domain Containing Receptor 3 (SORCS3) (C-Term) antibody

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Synonyms SORCS, 6330404A12Rik, AW045579
(3), (2), (1), (1), (1), (1), (1)
(21), (13), (13)
(16), (5)
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Immunohistochemistry (IHC), Western Blotting (WB)
(11), (11), (4), (3), (1)
Pubmed 3 references available
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Quantity 500 μg
Shipping to United States ( )
Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the c-terminal region of human SORCS3 conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 95% identity with mouse sequence.
Isotype IgG
Specificity Specific for SORCS3.
Alternative Name SORCS3 (SORCS3 Antibody Abstract)
Background This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins.
Subcellular location: Membrane, Single-pass type I membrane protein.
Tissue specificity: Highly expressed in brain. Also known as: SORCS 3, SORCS, Sortilin related VPS10 domain containing receptor 3, VPS10 domain containing receptor SorCS3, VPS10 domain receptor protein SORCS 3.
Research Area Neurology
Application Notes A concentration of 10-50 µg/ml is recommended.
The optimal concentration should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Deloukas, Earthrowl, Grafham et al.: "The DNA sequence and comparative analysis of human chromosome 10. ..." in: Nature, Vol. 429, Issue 6990, pp. 375-81, 2004 (PubMed).

Hampe, Rezgaoui, Hermans-Borgmeyer et al.: "The genes for the human VPS10 domain-containing receptors are large and contain many small exons." in: Human genetics, Vol. 108, Issue 6, pp. 529-36, 2001 (PubMed).

Kikuno, Nagase, Ishikawa et al.: "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 6, Issue 3, pp. 197-205, 1999 (PubMed).

Catalog No. ABIN350861
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