Transferrin antibody

Catalog No. ABIN356489

The Rabbit Polyclonal anti-Transferrin antibody is suitable to detect Transferrin in samples from Human. It has been validated for IP and EIA.

Quick Overview for Transferrin antibody (ABIN356489)

Target: Transferrin (TF)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Transferrin antibody is un-conjugated

Application: Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Product Details anti-Transferrin Antibody

Specificity: This antibody is specific for Transferrin (TF).

Purification: Protein A Chromatography.

Immunogen: Purified human transferrin.

Isotype: IgG

Application Details

Application Notes: Suitable for use in Immunoprecipitation and ELISA (1/1,000-1/10,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 2.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.05 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for Transferrin

Target: Transferrin (TF)

Background: Transferrin is a blood plasma protein for iron ion delivery. It is a is a glycoprotein, which binds iron very tightly but reversibly. Transferrin has a molecular weight of around 80 kilo Daltons and contains 2 specific high affinity Fe (III) binding sites. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/Transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. When a transferrin protein loaded with iron encounters a transferrin receptor on the surface of a cell (importantly, to erythroid precursors in the bone marrow), it binds to it and is consequently transported into the cell in a vesicle.Synonyms: Beta-1 metal-binding globulin, Serotransferrin, Siderophilin

Gene ID: 7018

NCBI Accession: NP_001054

UniProt: P02787

Pathways: Transition Metal Ion Homeostasis