Ubiquitination Factor E4A (UBE4A) (C-Term) antibody

Details for Product No. ABIN357482
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Antigen
Synonyms E4, UBOX2, UFD2, Ab2-232, 4732444G18Rik, 9930123J21Rik, UFD2b, ufd2, ubox2
Epitope
C-Term
(2), (2), (1), (1), (1), (1)
Reactivity
Human
(11), (4), (4), (2), (1), (1), (1), (1)
Host
Rabbit
(12), (2)
Clonality
Polyclonal
Application
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(14), (6), (2), (1), (1)
Pubmed 1 reference available
Catalog no. ABIN357482
Quantity 0.4 mL
Price
357.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human UBE4A.
Specificity This antibody detects UBE4A at C-term.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Alternative Name UBE4A
Background Ubiquitination requires a ubiquitin-activating enzyme, a ubiquitin-conjugating enzyme, and usually a substrate-specific ubiquitin-protein ligase. Multiubiquitination needs a fourth factor, to bind to the ubiquitin moieties of preformed conjugates and catalyze ubiquitin chain assembly in conjunction with the first three proteins.1 Human protein KIAA0126, with a predicted 1,073 amino acid residues, is a member of the novel protein family defined by ubiquitination conjugation factor E4.2 In yeast, E4 activity is linked to cell survival under stress conditions, indicating that eucaryotes use E4-dependent proteolysis pathways for multiple cellular functions.
Alternate names: KIAA0126, Ubiquitin conjugation factor E4 A
Molecular Weight 123537 Da
Gene ID 9354
NCBI Accession 5874
UniProt Q14139
Application Notes ELISA 1: 1,000. Western blot 1: 100 - 1: 200. Immunohistochemistry 1: 50 - 1: 100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Supplier Images
anti-Ubiquitination Factor E4A (UBE4A) (C-Term) antibody anti-Ubiquitination Factor E4A (UBE4A) (C-Term) antibody
anti-Ubiquitination Factor E4A (UBE4A) (C-Term) antibody (2) anti-Ubiquitination Factor E4A (UBE4A) (C-Term) antibody (Image 2)
Background publications Nagase, Seki, Tanaka et al.: "Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 2, Issue 4, pp. 167-74, 199-210, 1996 (PubMed).

Hosts (12), (2)
Reactivities (11), (4), (4), (2), (1), (1), (1), (1)
Applications (14), (6), (2), (1), (1)
Epitopes (2), (2), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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