CRK (pSer41) antibody
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Epitope
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN358272 |
| Quantity |
0.1 mg (0.25 mg/ml) |
| Price |
285.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: Proto-oncogene C-crk, p38, Adapter molecule crk
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Gene ID
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1398
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Swiss-Prot
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P46108
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Immunogen
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This antibody is generated from rabbits immunized with a KLH conjugated syntheticphosphopeptide corresponding to amino acid residues surrounding S41 of human CRK.
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Cross-Reactivity
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Human
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Isotype
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Ig (Matching secondary antibodies)
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Description
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CRK is a member of an adapter protein family that binds to severaltyrosine-phosphorylated proteins. It has several SH2 and SH3 domains (src-homologydomains) and is involved in several signaling pathways, recruiting cytoplasmic proteins inthe vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminalSH2 domain of this protein functions as a positive regulator of transformation whereas theC-terminal SH3 domain functions as a negative regulator of transformation.
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Specificity
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This antibody detects CRK pSer41. Predicted to cross react with Mouse (100% Antigen Homology). Species: Human. Others not tested. Add. Information: Molecular weight: 22906 Da
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Application Notes
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ELISA: 1/1,000. Dot Blot: 1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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0.25 mg/ml
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Purification
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Aff - Purified
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Buffer
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PBS with 0.09% (W/V) Sodium Azide as preservative.
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Storage
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures.
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Restrictions
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For Research Use only
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Alternatives for antigen "CRK", type "Antibodies"
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Hosts
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Rabbit (8), Mouse (6)
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Reactivities
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Human (14), Mouse (Murine) (1), Rat (Rattus) (1)
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Applications
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Western Blotting (WB) (9), Enzyme Immunoassay (EIA) (5), Dot Blot (Dot) (3), ELISA (Detection) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunocytochemistry (ICC) (2), Flow Cytometry (FACS) (1), Immunofluorescence (IF) (1), Immunoprecipitation (IP) (1)
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Epitopes
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pSer41 (1), pTyr221 (1)
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Alternatives 
