PIK3CD antibody (pTyr524)

Catalog No. ABIN358395

The Rabbit Polyclonal anti-PIK3CD antibody (ABIN358395) specifically detects PIK3CD in EIA. The antibody is reactive with Human samples.

Quick Overview for PIK3CD antibody (pTyr524) (ABIN358395)

Target: PIK3CD (Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIK3CD antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Product Details anti-PIK3CD Antibody

Binding Specificity: pTyr524

Specificity: This antibody detects PIK3CD pTyr524. Predicted to cross react with Mouse (100 % Antigen Homology).

Purification: Affinity purification in a 2-step procedure with the control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y524 of human PIK3CD.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Dot Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for PIK3CD

Target: PIK3CD (Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD))

Alternative Name: PIK3CD

Background: Phosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids. See MIM 602838. The class I PI3Ks display a broad phosphoinositide lipid substrate specificity and include p110-alpha , p110-beta, and p110-gamma. p110-alpha and p110-beta interact with SH2/SH3-domain-containing p85 adaptor proteins and with GTP-bound Ras.Synonyms: 5-bisphosphate 3-kinase catalytic subunit delta isoform, PI3-kinase subunit delta, PI3K-delta, Phosphatidylinositol-4, PtdIns-3-kinase subunit delta, PtdIns-3-kinase subunit p110-delta

Molecular Weight: 119479 Da

Gene ID: 5293, 9606

UniProt: O00329

Pathways: BCR Signaling, Warburg Effect