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Transforming Growth Factor beta Regulator 1 (TBRG1) (N-Term) antibody

Details for Product No. ABIN358981
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Antigen
Synonyms MGC89629, AA408552, AA409675, Niam, Tb-5, mFLJ00213, NIAM, TB-5
Epitope
N-Term
(5), (2), (1)
Reactivity
Human
(23), (14), (14), (12), (12), (12)
Host
Rabbit
(23)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(14), (10), (4), (3)
Pubmed 2 references available
Quantity 0.4 mL
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Catalog No. ABIN358981
357.50 $
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human TBRG1.
Specificity This antibody reacts to TBRG1.
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Alternative Name TBRG1 / NIAM
Background TBRG1 acts as a growth inhibitor. It can activate TP53/p53, cause G1 arrest and collaborate with CDKN2A to restrict proliferation, but it does not require either protein to inhibit DNA synthesis. TBRG1 redistributes CDKN2A into the nucleoplasm, and is involved in maintaining chromosomal stability.
Alternate names: Nuclear interactor of ARF and Mdm2, Transforming growth factor beta regulator 1
Gene ID 84897
NCBI Accession 9606
UniProt Q3YBR2
Application Notes ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Background publications Babalola, Schultz: "Modulation of gene expression in the preimplantation mouse embryo by TGF-alpha and TGF-beta." in: Molecular reproduction and development, Vol. 41, Issue 2, pp. 133-9, 1995 (PubMed).

Tompkins, Hagen, Frazier et al.: "A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability." in: The Journal of biological chemistry, Vol. 282, Issue 2, pp. 1322-33, 2007 (PubMed).

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