Transforming Growth Factor beta Regulator 1 (TBRG1) (N-Term) antibody

Details for Product No. ABIN358981
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Synonyms MGC89629, AA408552, AA409675, Niam, Tb-5, mFLJ00213, NIAM, TB-5
(12), (7), (2), (1)
(27), (16), (16), (1), (1), (1)
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(16), (10), (7), (3), (3)
Pubmed 2 references available
Quantity 0.4 mL
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human TBRG1.
Isotype Ig
Specificity This antibody reacts to TBRG1.
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Alternative Name TBRG1 / NIAM (TBRG1 Antibody Abstract)
Background TBRG1 acts as a growth inhibitor. It can activate TP53/p53, cause G1 arrest and collaborate with CDKN2A to restrict proliferation, but it does not require either protein to inhibit DNA synthesis. TBRG1 redistributes CDKN2A into the nucleoplasm, and is involved in maintaining chromosomal stability.Synonyms: Nuclear interactor of ARF and Mdm2, Transforming growth factor beta regulator 1
Gene ID 84897, 9606
UniProt Q3YBR2
Application Notes ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Transforming Growth Factor beta Regulator 1 (TBRG1) (N-Term) antibody (ABIN358981) Western blot analysis of anti-TBRG1 Pab in mouse kidney tissue lysates (35ug/lane). T...
Background publications Tompkins, Hagen, Frazier et al.: "A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability." in: The Journal of biological chemistry, Vol. 282, Issue 2, pp. 1322-33, 2007 (PubMed).

Babalola, Schultz: "Modulation of gene expression in the preimplantation mouse embryo by TGF-alpha and TGF-beta." in: Molecular reproduction and development, Vol. 41, Issue 2, pp. 133-9, 1995 (PubMed).

Catalog No. ABIN358981
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