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Platelet/endothelial Cell Adhesion Molecule (PECAM1) (C-Term) antibody

Details for Product No. ABIN359628
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Antigen
Synonyms CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM, C85791, Cd31, Pecam
Epitope
C-Term
(52), (12), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(378), (183), (67), (41), (30), (20), (11), (5), (2), (1)
Host
Rabbit
(290), (154), (79), (4), (4)
Clonality
Polyclonal
Conjugate
Un-conjugated
(55), (46), (30), (19), (9), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(294), (196), (116), (108), (97), (70), (60), (51), (36), (24), (19), (5), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Catalog No. ABIN359628
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This CD31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CD31.
Specificity This antibody recognizes CD31.
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Alternative Name CD31 / PECAM1
Background CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. It is also weakly expressed on many peripheral lymphoid cells and platelets. CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas). CD31 is a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions.
Alternate names: EndoCAM, GPIIA', PECAM-1, Platelet endothelial cell adhesion molecule
Gene ID 5175
NCBI Accession 9606
UniProt P16284
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes ELISA: 1/1,000. Western blotting: 1/50-1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Background publications Newman, Berndt, Gorski et al.: "PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily." in: Science (New York, N.Y.), Vol. 247, Issue 4947, pp. 1219-22, 1990 (PubMed).

Stockinger, Gadd, Eher et al.: "Molecular characterization and functional analysis of the leukocyte surface protein CD31." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 145, Issue 11, pp. 3889-97, 1991 (PubMed).

Simmons, Walker, Power et al.: "Molecular cloning of CD31, a putative intercellular adhesion molecule closely related to carcinoembryonic antigen." in: The Journal of experimental medicine, Vol. 171, Issue 6, pp. 2147-52, 1990 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN359628
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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