PLAUR antibody

Catalog No. ABIN360948

The Rat Monoclonal anti-PLAUR antibody (Clone 7J34) (ABIN360948) specifically detects PLAUR in WB. The antibody is reactive with Mouse samples.

Quick Overview for PLAUR antibody (ABIN360948)

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This PLAUR antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 7J34

Product Details anti-PLAUR Antibody

Specificity: This antibody detects uPAR.

Purification: Protein A/G Affinity Chromatography

Immunogen: Purified Mouse Recombinant uPAR

Isotype: IgG2

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Buffer: PBS, None

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PLAUR

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Alternative Name: CD87 / uPAR

Background: UPAR (Urokinase plasminogen activator receptor) is a glycoprotein I anchored surface receptor specific for urokinase plasminogen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum beta globulin plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a trypsin like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. uPA and uPAR are known to be overexpressed in mesenchymal and epithelial tumor cells and are required for tumor invasion and metastasis.Synonyms: MO3, Monocyte activation antigen Mo3, PLAUR, U-PAR, Urokinase plasminogen activator surface receptor

Gene ID: 18793

NCBI Accession: NP_035243

UniProt: P35456

Pathways: Inositol Metabolic Process