Immunohistochemistry on formalin-fixed paraffin embedded sections: dilute 1: 25-1: 50 inan ABC method (30 minutes at room temperature). Recommended Positive Control: Tonsil Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
SERPINA1
(serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))
Alternative Name
alpha-1-Antitrypsin
Background
Alpha 1 Antitrypsin is a plasma protein synthesised in the liver. It consists of a single polypeptide chain and has a molecular weight of 52 kDa. A serine protease inhibitor, its primary function is the protection of lung tissue from the action of neutrophil elastase.Synonyms: AAT, Alpha-1 protease inhibitor, Alpha-1-antiproteinase, SERPINA1