Thymidine Glycol antibody
The Mouse Monoclonal anti-Thymidine Glycol antibody is suitable to detect Thymidine Glycol in samples from Chemical. It has been validated for IHC.
Catalog No. ABIN361277
$814.63
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 9 to 13 Business Days
Quick Overview for Thymidine Glycol antibody (ABIN361277)
Target
Thymidine Glycol (TG)
Reactivity
Chemical
Host
Mouse
Clonality
Monoclonal
Conjugate
This Thymidine Glycol antibody is un-conjugated
Application
Immunohistochemistry (IHC)
Clone
2E8
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Specificity
- Specific to DNA containing thymidine glycol. Cross reactivity is checked to oxidized dC polymer, oxidized dG polymer and oxidized dA polymer.
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Immunogen
- Thymidine glycol polymer
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Isotype
- IgG1 kappa
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Application Notes
- Tested for IHC. User should determine optimum titer for each application.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- 100ug/ml
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Buffer
- 100?g/mL IgG in 10 mM Phosphate buffered saline, pH7.4 containing 1.0 % BSA
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Storage
- -20 °C
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- Thymidine Glycol (TG)
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Target Type
- Chemical
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Background
- Thymidineglycol (TG) is one of the major oxidation products of DNA. Thymidine (T) can be damaged by oxidative stress such as radiation and energy metabolism. Two different pathways to form TG have been suggested. Deoxythymidine in DNA is directly oxidised by hydroxy radical, to form TG. TG can be also formed through an intermediate thymidine chlorohydrin, which is derived from hypochlorous acid (HOCl) from neutrophil myeloperoxidase. Thymidineglycol is derived from DNA, not from RNA. TG is the oxidative stress marker secific for DNA damage.
Target
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