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Calcitonin-Related Polypeptide alpha (CALCA) antibody

Antigen

Calcitonin-Related Polypeptide alpha (CALCA)
Synonyms CALCA, CALC3, MGC152154, CT, KC, CGRP, CALC1, CGRP1, CGRP-I, MGC126648, CFP1, CGBP, SPP1, PCCX1, PHF18, hCGBP, HsT2645, 2410002I16Rik, 5830420C16Rik, CALC, calcitonin, calca, ci-ct
Clonality Monoclonal
Host
Alternatives

Mouse
Reactivity
Alternatives

Rat (Rattus), Human
Application
Alternatives Western Blotting (WB)
Catalog no. ABIN361373
Quantity 100 µl  (Variants)
Price 345.00 $   Plus shipping costs $35.00
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anti-Calcitonin-Related Polypeptide alpha (CALCA) antibody

Additional Information
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Alternative name Calcitonin Gene Related Peptide (CGRP)
Isotype IgG2a  (Matching secondary antibodies)
Description Calcitonin Gene Related Peptide [CGRP] is a 37 amino acid peptide and is the most potent endogenous vasodilator currently known (Brain et al.,1985). CGRP is primarily produced in nervous tissue, however, its receptors are expressed throughout the body. CGRP is also strongly implicated in the vasodilatory effect of endogenous cannabinoid anandamide in the brain. This effect was found to be antagonized by capsazepine. CGRP is also currently a major target of research in regards to factors effecting the onset of migraine headaches (Edvinsson L., 2003). CGRP antibodies have been used successfully in immunoneutralization (Wong et al., 1993)
Specificity Specific for Calcitonin Gene Related Peptide. Also recognizes rat beta-CGRP and human alpha-CGRP (10-fold less sensitivity compared to rat alpha-CGRP). Suggested positive controls are dorsal root ganglia, pancreas and gut. Notes: This antibody is an excellent tool for immunohistochemistry and for multiple labeling immunofluorescence of peripheral tissue like stomach, intestine, pancreas, sensory ganglia, and all the regions of the body that are innervated by primary afferent neurons as well as central nervous tissue. It is expected that the antibody will react with most mammals.

Application Details
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Application Notes Recommended Dilution: ICC: 1:50-1:100 Quality Control: ICC performed on each lot.
Purification Protein G purified
Storage Store at -20 °C, stable for 1 year
Research Area Hormones
Restrictions For Research Use only

Alternatives
Application Details Images Secondary Antibodies Variants back to top

Alternatives for antigen "Calcitonin-Related Polypeptide alpha (CALCA)", type "Antibodies"
Hosts Rabbit (93), Mouse (23), Goat (7), Sheep (5), Chicken (2), Guinea Pig (2)
Reactivities Human (117), Rat (Rattus) (35), Dog (Canine) (27), Mouse (Murine) (20), Pig (Porcine) (10), Sheep (Ovine) (10), Monkey (7), Rabbit (7), Hamster (6), Cow (Bovine) (3), Mammalian (3), Horse (Equine) (2), Chicken (1), Guinea Pig (1), Reptile (1), Zebrafish (Danio rerio) (1)
Applications Immunofluorescence (IF) (47), Flow Cytometry (FACS) (36), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (36), Enzyme Immunoassay (EIA) (27), Western Blotting (WB) (24), Immunohistochemistry (Frozen Sections) (IHC (fro)) (22), Radioimmunoassay (RIA) (21), ELISA (13), Immunohistochemistry (IHC) (10), Immunoprecipitation (IP) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (4), Electrophoresis (EP) (3), ELISA (Capture) (2), ELISA (Detection) (2), Immunoelectron Microscopy (IEM) (2)
Conjugates Biotin (6), Alexa Flour 488 (2), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), FITC (2), Gold (2), HRP (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2), RBITC (2)
Epitopes AA 1-32 (6), C-Term (2)