CPI-17 antibody (AA 36-40)

Catalog No. ABIN362987

The Rabbit Polyclonal anti-CPI-17 antibody is suitable to detect CPI-17 in samples from Human, Mouse and Rat. It has been validated for IF.

Quick Overview for CPI-17 antibody (AA 36-40) (ABIN362987)

Target: CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPI-17 antibody is un-conjugated

Application: Immunofluorescence (IF)

Product Details anti-CPI-17 Antibody

Binding Specificity: AA 36-40

Specificity: The antibody detects endogenous level of total CPI17a protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

Immunogen: Peptide sequence around AA 36-40 (R-V-T-V-K) derived from Human CPI17a. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Isotype: IgG

Application Details

Application Notes: Immunofluorescence: 1:100-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for CPI-17

Target: CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))

Alternative Name: CPI17alpha

Background: Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.

Molecular Weight: 17 kDa

NCBI Accession: NP_150281

UniProt: Q96A00