Latency-Associated Nuclear Antigen 2 (LANA2) antibody

Catalog No. ABIN363228

The Mouse Monoclonal anti-Latency-Associated Nuclear Antigen 2 (LANA2) antibody (Clone CM-A807) (ABIN363228) specifically detects Latency-Associated Nuclear Antigen 2 (LANA2) in IF, IP, IHC, ELISA and WB. The antibody is reactive with Kaposi's sarcoma-associated herpesvirus (KSHV) samples.

Quick Overview for Latency-Associated Nuclear Antigen 2 (LANA2) antibody (ABIN363228)

Target: Latency-Associated Nuclear Antigen 2 (LANA2)

Reactivity: Kaposi's sarcoma-associated herpesvirus (KSHV)

Host: Mouse

Clonality: Monoclonal

Application: Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Clone: CM-A807

Product Details

Specificity: Reacts with human and murin Kaposi's sarcoma-associated herpes virus (KSHV) ~66-70 kDa LANA2 protein and shows no cross-reactivity to cellular proteins

Purification: Purified (protein G)

Immunogen: Recombinant LANA2 fusion protein

Isotype: IgG1 kappa

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/10 to1/2000 - IF : 2 to 4 μg/mL - IP : 2 to 4 μg/mL - WB : 2 to 4 μg/mL

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Storage: 4 °C/-20 °C

Storage Comment: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 6 months

Target Details

Target: Latency-Associated Nuclear Antigen 2 (LANA2)

Target Type: Viral Protein

Background: LANA2 (latency-associated nuclear antigen) is an inhibitor of p53-induced transcription in reporter assays and may be an apoptosis antagonist.It is a nuclear protein associated with Kaposi's sarcoma-associated herpes virus (KSHV), or human herpes virus 8.It is found in abundance in the nuclei of cultured cells from KSHV-infected hematopoietic tissues, such as PEL (primary effusion lymphoma) and CD (multicentric Castleman's disease).It does not appear to be expressed in KS (Kaposi's sarcoma) lesions.