PLTP antibody

Catalog No. ABIN363330

The Rabbit Polyclonal anti-PLTP antibody (ABIN363330) specifically detects PLTP in WB, IHC, ICC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for PLTP antibody (ABIN363330)

Target: PLTP (Phospholipid Transfer Protein (PLTP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLTP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-PLTP Antibody

Specificity: Reacts with PLTN from human and mouse

Purification: Antiserum

Immunogen: A partial peptide of human PLTP

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
- WB : 1/500 - IHC - P : 1/500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: , Sodium azide 0.02 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C/-80 °C

Storage Comment: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Target Details for PLTP

Target: PLTP (Phospholipid Transfer Protein (PLTP))

Background: PLTP (phospholipid transfer protein) belongs to lipid transfer/lipopolysaccharide-binding proteins (BPI/LBP) family and it is a monomeric sectered protein expressed ubiquitously with highest expression in liver, one of the major sites of lipoprotein production and degradation. PLTP converts HDL into larger and smaller particles, and play a key role in extracellular phospholipid transport as well as modulation of HDL particles. Plasma PLTP is also considered a nonspecific lipid transfer protein because, along with phospholipids, it can also transfer alpha-tocopherol, diacylglycerol, cerebroside, and lipopolysaccharides. PLTP deficient mice depicts lowered susceptibility for atherosclerosis, whereas, PLTP transgenic mice have more atherosclerosis. In humans, an increased PLTP activity been linked to several conditions including type I/II diabetes mellitus, metabolic syndrome, obesitas, increased risk of coronary artery disease and cardiovascular disease.

Pathways: Lipid Metabolism