Salmonella O-Antigens antibody
Quick Overview for Salmonella O-Antigens antibody (ABIN363831)
Target
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Recognizes the O antigen of Salmonella enterica, serovar paratyphi A (also known as S. paratyphi). The O antigen is a polysaccharide that extends from the core oligosaccharide, which itself is attached to lipid A. These three components together form the lipopolysaccharide (LPS), a major component of the outer membrane of Gram-negative bacteria. The LPS is an endotoxin and induces a strong immune response from the host. Its mutation or removal results in the death of the bacterial cell and as such is a prime target for antimicrobial drugs. The O antigen is the outermost component of the LPS and functions as a receptor for bacteriophages. It is also important in the immune response of the host. Considerable diversity is seen within Salmonella O antigens. Salmonella enterica, serovar paratyphi A belongs to serogroup A of Salmonella and causes paratyphoid fever, which is similar to typhoid fever but more benign. Specific for the 0-2 antigenic determinant of Salmonella serogroup A and does not cross-react with the LPS of serogroups B, D or E of Salmonella spp.
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Purification
- Affinity purified
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Immunogen
- Heat inactivated cells of Salmonella paratyphi A.
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Target Species of Antibody: Salmonella
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
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Short term: -20°C
Long term: -20°C.
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- Salmonella O-Antigens
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Alternative Name
- Salmonella O Antigens
Target
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