MHC Class II I-Ab antibody
Quick Overview for MHC Class II I-Ab antibody (ABIN371140)
Target
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Characteristics
- Synonyms: H2-Eb1, H-2 class II histocompatibility antigen I-A beta chain
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Endotoxin Level
- Low Endotoxin
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Isotype
- IgG2b
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anti-MHC Class II I-Ab antibody
Reactivity: Mouse FACS Host: Mouse Monoclonal 25-9-3 unconjugated
anti-MHC Class II I-Ab antibody (PE)Reactivity: Mouse FACS Host: Mouse Monoclonal 25-9-3 PE
anti-MHC Class II I-Ab antibody (Biotin)Reactivity: Mouse FACS Host: Mouse Monoclonal 25-9-3 Biotin
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Application Notes
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Flow Cytometry. Complement-dependent Cytotoxicity Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS without preservatives.
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Preservative
- Without preservative
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Storage
- -20 °C
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Storage Comment
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Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Expiry Date
- 12 months
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- MHC Class II I-Ab
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Background
- MHC Class II antigens are heterodimers consisting of one alpha chain(31-34kD) and one beta chain (26-29kD). The family of monoclonal antibodies (ER-TR 3, ER-TR 2, ER-TR 1) detect MHC class II antigens encoded by the murine Ia region of the H-2 complex, corresponding to the human HLA-DR region. MHC Class II antigens are a valuable tool for studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these antibodies also stain stromal cells in the thymus. MHC Class II antigens are also inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma.Synonyms: H-2 class II histocompatibility antigen I-A beta chain, H2-Eb1
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UniProt
- P18468
Target
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