MHC Class II I-Ab antibody (PE)
Quick Overview for MHC Class II I-Ab antibody (PE) (ABIN371148)
Target
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Characteristics
- Synonyms: H2-Eb1, H-2 class II histocompatibility antigen I-A beta chain
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Immunogen
- C3H. SW splenocytes. (Ref. 1)
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Isotype
- IgM
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anti-MHC Class II I-Ab antibody
Reactivity: Mouse FACS Host: Mouse Monoclonal 25-9-3 unconjugated
anti-MHC Class II I-Ab antibody (PE)Reactivity: Mouse FACS Host: Mouse Monoclonal 25-9-3 PE
anti-MHC Class II I-Ab antibody (Biotin)Reactivity: Mouse FACS Host: Mouse Monoclonal 25-9-3 Biotin
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Application Notes
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Flow Cytometry: < / = 0.2 μg/10^6 cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.1 mg/mL
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Buffer
- PBS containing 0.09 % Sodium Azide as preservative and a stabilizing agent.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
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Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Expiry Date
- 12 months
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- MHC Class II I-Ab
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Background
- MHC Class II antigens are involved in antigen presentation by Antigen Presenting Cells (APCs) to CD4+ T cells. They are constitutively expressed on APCs including B cells, macrophages, monocytes and dendritic cells, and are inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma. The Mouse H2 Ab locus is orthologous to human DQB, which varies from typical class II genes in that both the alpha and beta chains are polymorphic.Synonyms: H-2 class II histocompatibility antigen I-A beta chain, H2-Eb1
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UniProt
- P18468
Target
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