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Antibodies
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anti-Adenosine Monophosphate Deaminase 1 (AMPD1) (AA 500-550) antibody
Adenosine Monophosphate Deaminase 1 (AMPD1) (AA 500-550) antibody
| Antigen |
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| Synonyms |
AMPD1, ampd1, MAD, MADA, Ampd-1, AI553520 |
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Epitope
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AA 500-550
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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 Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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| Catalog no. |
ABIN372278 |
| Quantity |
50 µg (0.5 mg/ml) |
| Price |
390.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: Myoadenylate deaminase, AMP deaminase isoform M
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Alternative name
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AMP deaminase 1 / AMPD1
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Swiss-Prot
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P23109
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Immunogen
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Synthetic peptide corresponding to a portion of the amino acids 500-550 of Human AMPD1.
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Cross-Reactivity
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Cow (Bovine), Chimpanzee, Human, Monkey, Mouse (Murine), Rat (Rattus)
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Isotype
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IgG (Matching secondary antibodies)
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Description
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AMP deaminase (AMPD) is an allosteric enzyme that plays a critical role in energymetabolism. There are three functional isoforms of AMPD. AMPD1 is the skeletalmuscle-specific isoform M located in type II muscle fibers, neuromuscular junctions and incapillaries. Defects in AMPD1 are the cause of adenosine monophosphate deaminasedeficiency muscle type (AMPDDM). AMPDDM is a metabolic disorder resulting inexercise-related myopathy. It is characterized by exercise-induced muscle aches, cramps,and early fatigue.
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Specificity
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This antibody recognizes AMPD1. Species Reactivity: Tested: Human. Expected from sequence similarity: Bovine, Chimpanzee, Monkey, Mouse, Rat andZebrafish. Add. Information: Predicted Molecular Weight: 87 kDa.
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Application Notes
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Immunohistochemistry on Paraffin Sections: 5-10 µg/ml. Western Blot: 0.5-2.0 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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0.5 mg/ml
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Purification
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Aff - Purified
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Buffer
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PBS containing 0.05% Sodium Azide as preservative and 0.2% Gelatin asstabilizer.
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Storage
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Restrictions
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For Research Use only
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Alternatives for antigen "Adenosine Monophosphate Deaminase 1 (AMPD1)", type "Antibodies"
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Hosts
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Rabbit (4), Goat (3)
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Reactivities
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Human (4), Mouse (Murine) (3), Rat (Rattus) (3), Cow (Bovine) (2), Monkey (2), Dog (Canine) (1)
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Applications
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ELISA (3), Immunohistochemistry (IHC) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Western Blotting (WB) (2), Enzyme Immunoassay (EIA) (1)
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