PLTP antibody

Catalog No. ABIN372781

This Rabbit Polyclonal antibody specifically detects PLTP in WB, IHC (p) and IHC (fro). It exhibits reactivity toward Human and Mouse.

Quick Overview for PLTP antibody (ABIN372781)

Target: PLTP (Phospholipid Transfer Protein (PLTP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLTP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PLTP Antibody

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Protein G Chromatography.

Immunogen: Synthetic peptide surrounding amino acid 473 of Human PLTP

Isotype: IgG

Application Details

Application Notes: Western Blot: 1/200-1/1000. Immunohistochemistry on Frozen Sections: 1/50. Immunohistochemistry on Paraffin Sections: 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS containing 1 % BSA as stabilizer and 0.02 % as Thimerosal as preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody at-20 °C for Short term or at -70 °C for Long term.

Target Details for PLTP

Target: PLTP (Phospholipid Transfer Protein (PLTP))

Alternative Name: PLTP

Background: PLTP is one of at least two lipid transfer proteins found in human plasma. This protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, it may be involved in cholesterol metabolism. Plasma phospholipid transfer protein (PLTP) plays a central role in regulating plasma HDL levels and distribution of HDL subpopulations. This regulation is evidenced in vivo by markedly reduced plasma HDL levels in PLTP gene knock-out mice. PLTP also facilitates free cholesterol influx into HDL.Synonyms: Lipid Transfer Protein II, Phospholipid Transfer Protein

NCBI Accession: NM_006227

UniProt: P55058

Pathways: Lipid Metabolism