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Antibodies
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anti-Apolipoprotein E (APOE) (C-Term) antibody
Apolipoprotein E (APOE) (C-Term) antibody
| Antigen |
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| Synonyms |
AD2, LPG, LDLCQ5, MGC1571, AI255918, APOEA, APOE, ad2, apoprotein, MGC110064, im:7036787, wu:fb69a05, zgc:110064, apoe |
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Epitope
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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 Alternatives Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Western Blotting (WB) (45), Enzyme Immunoassay (EIA) (22), ELISA (18), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (10), Immunohistochemistry (Frozen Sections) (IHC (fro)) (8), Immunodiffusion (ID) (6), Immunohistochemistry (IHC) (6), Radioimmunoassay (RIA) (6), Immunoprecipitation (IP) (5), Immunoelectrophoresis (IEP) (2), Radial Immunodiffusion (RID) (2), Dot Blot (Dot) (1), Flow Cytometry (FACS) (1), Ouchterlony Double Diffusion (ODD) (1), Thin Layer Immunoassay (TIA) (1), To be determined by user (TBD) (1)
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| Catalog no. |
ABIN374539 |
| Quantity |
0.1 mg (0.5 mg/ml) (Variants) |
| Price |
290.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: ApoE, Apo-E
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Alternative name
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Apolipoprotein E (Apo E)
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Gene ID
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348
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Swiss-Prot
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P02649
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Immunogen
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Peptide with sequence C-VGTSAAPVPSDNH, from the C Terminus of the protein sequence
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Cross-Reactivity
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Human
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Description
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Apolipoprotein E is essential for the normal catabolism of triglyceride rich lipoproteinconstituents. The apolipoprotein E gene is mapped to chromosome 19 in a cluster withAPOC1 and APOC2. Defects in Apolipoprotein E result in familial dysbetalipoproteinemia, ortype III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol andtriglycerides are the consequence of impaired clearance of chylomicron and VLDLremnants. Mutations in the APOE gene confer susceptibility to Alzheimer's disease byaffecting amyloid-beta deposition.
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Specificity
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This antibody reacts to Apolipoprotein E. Species Reactivity: Tested: Human, Chimpanzee
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Application Notes
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Peptide ELISA: 1/32000. Western blot: 0.1 - 0.3 µg/ml. Immunohistochemistry on paraffin sections: 2 - 4 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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0.5 mg/ml
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Purification
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Aff - Purified
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Buffer
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Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
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Storage
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Restrictions
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For Research Use only
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Alternatives for antigen "Apolipoprotein E (APOE)", type "Antibodies"
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Hosts
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Goat (31), Rabbit (21), Mouse (15)
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Reactivities
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Human (43), Mouse (Murine) (4), Rabbit (4), Hamster (3), Rat (Rattus) (2), Chimpanzee (1)
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Applications
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Western Blotting (WB) (45), Enzyme Immunoassay (EIA) (22), ELISA (18), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (10), Immunohistochemistry (Frozen Sections) (IHC (fro)) (8), Immunodiffusion (ID) (6), Immunohistochemistry (IHC) (6), Radioimmunoassay (RIA) (6), Immunoprecipitation (IP) (5), Immunoelectrophoresis (IEP) (2), Radial Immunodiffusion (RID) (2), Dot Blot (Dot) (1), Flow Cytometry (FACS) (1), Ouchterlony Double Diffusion (ODD) (1), Thin Layer Immunoassay (TIA) (1), To be determined by user (TBD) (1)
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Conjugates
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Biotin (3), HRP (1)
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Epitopes
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C-Term (3)
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