FCGR2A antibody (C-Term)

Catalog No. ABIN374540

The Goat Polyclonal anti-FCGR2A antibody is suitable to detect FCGR2A in samples from Human. It has been validated for WB.

Quick Overview for FCGR2A antibody (C-Term) (ABIN374540)

Target: FCGR2A (Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This FCGR2A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FCGR2A Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to CD32.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-PDALEEPDDQNRI, from the C Terminus of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/16000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FCGR2A

Target: FCGR2A (Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A))

Alternative Name: CD32 / FcRII-A

Background: CD32 is a receptor for the Fc region of complexed or aggregated immunoglobulins gamma. This is a low affinity receptor. It is Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B cells. Binding to this receptor results in downmodulation of previous state of cell activation triggered via antigen receptors on B cells (BCR), T cells (TCR) or via another Fc receptor.Synonyms: CDw32, FCG2, FCGR2A, FCGR2A1, Fc-gamma RII-a, Fc-gamma-RIIa, IGFR2, IgG Fc receptor II, Low affinity immunoglobulin gamma Fc region receptor II

Gene ID: 2212, 9606

UniProt: P12318