Adenosine A2b Receptor antibody (C-Term)

Catalog No. ABIN374607

The Goat Polyclonal anti-Adenosine A2b Receptor antibody (ABIN374607) specifically detects Adenosine A2b Receptor in IHC (p) and EIA. The antibody is reactive with Human samples.

Quick Overview for Adenosine A2b Receptor antibody (C-Term) (ABIN374607)

Target: Adenosine A2b Receptor (ADORA2B)

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Adenosine A2b Receptor antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-Adenosine A2b Receptor Antibody

Binding Specificity: C-Term

Sequence: CQADVKSGNG Q

Specificity: This anitbody recognizes Adenosine receptor A2b.

Purification: Affinity chromatography

Immunogen: Peptide with sequence from the C Terminus of the protein sequence (NP_000667.1). Genename: ADORA2B

Application Details

Application Notes: Peptide ELISA: 1/4000. Western Blot. Immunohistochemistry on paraffin sections: 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Adenosine A2b Receptor

Target: Adenosine A2b Receptor (ADORA2B)

Alternative Name: Adenosine Receptor A2b

Background: Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The adenosine receptors, including adenosine A1-R, adenosine A2A-R, adenosine A2B-R, and adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthasis and total protein synthesis are inhibited in certain cells by adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNFα and blocks the endotoxin CD14 receptor signal transduction pathway.Synonyms: ADORA2B

Gene ID: 136, 9606

UniProt: P29275

Pathways: cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process