Moesin antibody (Internal Region)

Catalog No. ABIN374709

The Goat Polyclonal anti-Moesin antibody (ABIN374709) specifically detects Moesin in WB and EIA. The antibody is reactive with Human, Rat, Mouse and Dog samples.

Quick Overview for Moesin antibody (Internal Region) (ABIN374709)

Target: Moesin (MSN)

Reactivity: Human, Rat, Mouse, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This Moesin antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Moesin Antibody

Binding Specificity: Internal Region

Sequence: C-NARDESKKTA ND

Specificity: This antibody recognizes Moesin (Internal).

Cross-Reactivity (Details): Species reactivity (expected):Rat, Canine.
Species reactivity (tested):Human, Mouse.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_002435.1. Genename: MSN

Application Details

Application Notes: ELISA: 1/16000. Western 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Moesin

Target: Moesin (MSN)

Alternative Name: Moesin

Background: Moesin is a member of the ERM (Ezrin-Radixin-Moesin) protein family, which possesses structural and probably functional relationships, they function as plasma membrane-actin cytoskeleton linkers and participate in the formation of specialized domains of the plasma membrane and are all localized to the submembranous cytoskeleton. Moesin is widely expressed in different tissues in cells, where it is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signalling and for cell movement. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the submembraneous actin cytoskeleton. It is expressed in macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. It is involved in cell adhesion, migration and organization of cell surface structures.Synonyms: MSN, Membrane-organizing extension spike protein

Gene ID: 4478, 9606

UniProt: P26038

Pathways: Asymmetric Protein Localization