IDS antibody (Internal Region)

Catalog No. ABIN375037

This Goat Polyclonal antibody specifically detects IDS in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for IDS antibody (Internal Region) (ABIN375037)

Target: IDS (Iduronate 2-Sulfatase (IDS))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This IDS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IDS Antibody

Binding Specificity: Internal Region

Sequence: C-KHFRFRDLEE DP

Specificity: This antibody is expected to recognize isoform a of IDS (NP_000193.1).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of Human IDS (NP_000193.1). Genename: IDS

Application Details

Application Notes: Peptide ELISA: 1/16000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IDS

Target: IDS (Iduronate 2-Sulfatase (IDS))

Alternative Name: IDS / SIDS

Background: Iduronate 2 sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Defects in IDS are the cause of mucopolysaccharidosis type II (MPS-II) also known as Hunter syndrome. There are two named isoforms.Synonyms: Alpha-L-iduronate sulfate sulfatase, Iduronate 2-sulfatase, Idursulfase

Gene ID: 3423

NCBI Accession: NP_000193

UniProt: P22304

Pathways: Glycosaminoglycan Metabolic Process