KIT antibody

Catalog No. ABIN375629

Product Details anti-KIT Antibody

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reactivity: Chicken

Host: Mouse

Clonality: Monoclonal

Conjugate: This KIT antibody is un-conjugated

Application: Flow Cytometry (FACS)

Specificity: Chicken c-Kit, Mr 145 kDa

Characteristics: Mouse Anti-Chicken c-Kit-UNLB

Purification: Purified

Immunogen: Sp/chkit4A4 cells (Sp2/0 cells transfected with chicken c-Kit cDNA)

Clone: Kit2c75

Isotype: IgG2a

Application Details

Application Notes:

• Applications: FC - Quality tested
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and BIOT conjugates 1 g/106 cells PE conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Sample Volume: 1 mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Preservative: Without preservative

Handling Advice: Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: Store at 2-8°C

Target Details for KIT

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Alternative Name: c-Kit (KIT Products)

Background: C-Kit is a 145 kDa transmembrane receptor-type protein tyrosine kinase encoded by the c-Kit proto-oncogene and is the receptor for stem cell factor (SCF). c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. The amino acid sequence of chicken c-kit shows 63 % identity to mouse c-Kit and exhibits similar expression patterns in RNA blot analysis suggesting similar biological roles.

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity