CD24 antibody

Catalog No. ABIN376378

This Rat Monoclonal antibody specifically detects CD24 in FACS and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for CD24 antibody (ABIN376378)

Target: CD24 (CD24 Molecule (CD24))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD24 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 91

Product Details anti-CD24 Antibody

Purpose: Rat Anti-Mouse CD24-LE/AF

Specificity: Mouse CD24, Mr 35-45 kDa

Characteristics: Low Endotoxin/Azide Free Anti-Mouse CD24 antibody for use in flow cytometry and immunohistochemistry assays.

Endotoxin Level: Low Endotoxin

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Preservative: Azide free

Handling Advice: Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: 2-8°C

Target Details for CD24

Target: CD24 (CD24 Molecule (CD24))

Alternative Name: CD24

Background: CD24, also known as heat stable antigen, is a phosphatidylinositol-linked cell surface glycoprotein that is expressed at all stages of B cell development and on most thymocytes. The absence of expression from mature T cells is closely associated with their maturation from CD4 + CD8 + CD24 + thymocytes to either CD4 + CD8 - CD24 - or CD4 - CD8 + CD24 - T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. Its ligand is P-selectin (CD62P). 7 CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes.

Gene ID: 12484

UniProt: P24807

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation