Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1) antibody (FITC)

Antigen: Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1)

Synonyms: TM7LN3, EMR1

Clonality: Monoclonal (BM8)

Host: Rat

Reactivity: Mouse (Murine)

Conjugate: FITC

Catalog no.: ABIN380053

Additional Information

Alternative name: EMR1

Swiss-Prot: Q14246

Immunogen: cultured macrophages

Clone: BM8

Description: Gene: EMR1, Standard Gene Symbol: EMR1, Family: GPCR, Subfamily: Orphan-B, Synonyms: EMR1, F4/80, TM7LN3

Specificity: The antigen is a 125kD extracellular membrane protein sensitive to 2-mercaptoethanol. Antigen distribution: Isolated Cells: The antigen is expressed in vitro on over 80% of M-CSF stimulated bone marrow derived macrophages, after a few days of culture. It is absent from granulocytes, lymphocytes and thrombocytes. Tissue Sections: The antigen is detected on tissue fixed macrophages in all organs tested so far (spleen, lymph nodes, thymus, liver, skin) except lung. It is also present on Langerhans cells in the skin and Kupffer cells in the liver. In complete Freund's adjuvant induced granulomas, the antigen is expressed by inflammatory macrophages, but is absent from epitheloid cells. Specificity: Mouse: major subpopulation of resident tissue macrophages Other: human heart macrophages Predicted Reactivities: Mouse (Murine).

Application Details

Purification: Affinity Purified

Buffer: PBS pH 7.2, 10mg/ml BSA, 0.09% sodium azide

Storage: Store at 4°C.

Restrictions: For Research Use only