F4/80 antibody (FITC)

Catalog No. ABIN380053

This Rat Monoclonal antibody specifically detects F4/80 . It exhibits reactivity toward Mouse.

Quick Overview for F4/80 antibody (FITC) (ABIN380053)

Target: F4/80 (EMR1) (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This F4/80 antibody is conjugated to FITC

Application: Please inquire

Clone: BM8

Product Details anti-F4/80 Antibody (FITC)

Specificity: The antigen is a 125kD extracellular membrane protein sensitive to 2-mercaptoethanol. Antigen distribution: Isolated Cells: The antigen is expressed in vitro on over 80 % of M-CSF stimulated bone marrow derived macrophages, after a few days of culture. It is absent from granulocytes, lymphocytes and thrombocytes. Tissue Sections: The antigen is detected on tissue fixed macrophages in all organs tested so far (spleen, lymph nodes, thymus, liver, skin) except lung. It is also present on Langerhans cells in the skin and Kupffer cells in the liver. In complete Freund's adjuvant induced granulomas, the antigen is expressed by inflammatory macrophages, but is absent from epitheloid cells. Specificity: Mouse: major subpopulation of resident tissue macrophages Other: human heart macrophages

Purification: Affinity purified

Immunogen: Cultured macrophages.

Type of Immunogen: Cells

Application Details

Application Notes: Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS  pH 7.2, 10 mg/mL BSA, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4°C.

Target Details for F4/80

Target: F4/80 (EMR1) (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1))

Alternative Name: ADGRE1 / EMR1

Background: Name/Gene ID: ADGRE1
Subfamily: Orphan-B
Family: GPCR

Synonyms: ADGRE1, EMR1 hormone receptor, F4/80, EGF-like module receptor 1, TM7LN3, EMR1

Gene ID: 2015

UniProt: Q14246