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Details for Product No. ABIN387769

Chloride Intracellular Channel 4 (CLIC4) antibody

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Synonyms CLIC4L, H1, MTCLIC, huH1, p64H1, cb142, wu:fb33c05, wu:fc30h10, D0Jmb3, TU-74, mc3s5, mtCLIC, xclic4, clic4, MGC89006, MGC79614, CLIC4, DKFZp459A0325
»Alternatives Human
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 5 references available
Catalog no. ABIN387769
Quantity 0.1 mL
291.50 $   Plus shipping costs $45.00
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Immunogen Purified His-tagged CLIC4 protein was used to produced this monoclonal antibody.
Clone 17CT9-2-8
Isotype IgG1 kappa
Specificity Purified His-tagged CLIC4 protein was used to produced this monoclonal antibody.
Purification Ascites
Alternative Name CLIC4
Background Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family, the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells).
Synonyms: Chloride intracellular channel protein 4, Intracellular chloride ion channel protein p64H1, CLIC4
Molecular Weight 29 kDA
Gene ID 25932
UniProt NP_039234
Research Area Stem Cells, Cell Signaling, Cell Structure
Application Notes Recommend dilutions: WB : 1:2000,IHC : 1:50-100
Restrictions For Research Use only
Format Liquid
Buffer Crude ascites with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Yao, Qu, Yang et al.: "CLIC4 mediates TGF-beta1-induced fibroblast-to-myofibroblast transdifferentiation in ovarian cancer." in: Oncology reports, Vol. 22, Issue 3, pp. 541-8, 2009 (PubMed).

Spiekerkoetter, Guignabert, de Jesus Perez et al.: "S100A4 and bone morphogenetic protein-2 codependently induce vascular smooth muscle cell migration via phospho-extracellular signal-regulated kinase and chloride intracellular channel 4." in: Circulation research, Vol. 105, Issue 7, pp. 639-47, 13 p following 647, 2009 (PubMed).

Ponsioen, van Zeijl, Langeslag et al.: "Spatiotemporal regulation of chloride intracellular channel protein CLIC4 by RhoA." in: Molecular biology of the cell, Vol. 20, Issue 22, pp. 4664-72, 2009 (PubMed).

Li, Li, Jiang et al.: "Mutation detection in candidate genes for benign familial infantile seizures on a novel locus." in: The International journal of neuroscience, Vol. 120, Issue 3, pp. 217-21, 2010 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Alternatives for antigen "Chloride Intracellular Channel 4 (CLIC4)", type "Antibodies"
Hosts (49), (8), (3)
Reactivities (47), (31), (30), (16), (12), (11), (11), (1), (1), (1)
Applications (50), (37), (20), (17), (9), (9), (6), (6)
Conjugates (5), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (13), (6)