Chloride Intracellular Channel 4 (CLIC4) antibody

Details for Product No. ABIN387769
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Antigen
Reactivity
Human
(54), (35), (34), (16), (12), (11), (11), (1), (1), (1)
Host
Mouse
(53), (8), (3)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(5), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(52), (38), (23), (18), (10), (9), (7), (6), (1)
Pubmed 5 references available
Quantity 0.1 mL
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Availability Discontinued
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Catalog No. ABIN387769
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Immunogen Purified His-tagged CLIC4 protein was used to produced this monoclonal antibody.
Clone 17CT9-2-8
Isotype IgG1 kappa
Specificity Purified His-tagged CLIC4 protein was used to produced this monoclonal antibody.
Purification Ascites
Alternative Name CLIC4
Background Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family, the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells).
Synonyms: Chloride intracellular channel protein 4, Intracellular chloride ion channel protein p64H1, CLIC4
Molecular Weight 29 kDA
Gene ID 25932
NCBI Accession NP_039234
Research Area Stem Cells, Cell Signaling, Cell Structure
Application Notes WB = 1:2000, IHC = 1:50-100
Restrictions For Research Use only
Format Liquid
Buffer Crude ascites with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Chloride Intracellular Channel 4 (CLIC4) antibody Western blot analysis of anti-CLIC4 Monoclonal Antibody (ABIN387769) in Hela cell line lysates. CLIC4(arrow) was detected using the ascites Mab. Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with CLIC4 Antibody (ABIN387769), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
anti-Chloride Intracellular Channel 4 (CLIC4) antibody (2) anti-Chloride Intracellular Channel 4 (CLIC4) antibody (Image 2)
Background publications Yao, Qu, Yang et al.: "CLIC4 mediates TGF-beta1-induced fibroblast-to-myofibroblast transdifferentiation in ovarian cancer." in: Oncology reports, Vol. 22, Issue 3, pp. 541-8, 2009 (PubMed).

Spiekerkoetter, Guignabert, de Jesus Perez et al.: "S100A4 and bone morphogenetic protein-2 codependently induce vascular smooth muscle cell migration via phospho-extracellular signal-regulated kinase and chloride intracellular channel 4." in: Circulation research, Vol. 105, Issue 7, pp. 639-47, 13 p following 647, 2009 (PubMed).

Ponsioen, van Zeijl, Langeslag et al.: "Spatiotemporal regulation of chloride intracellular channel protein CLIC4 by RhoA." in: Molecular biology of the cell, Vol. 20, Issue 22, pp. 4664-72, 2009 (PubMed).

Li, Li, Jiang et al.: "Mutation detection in candidate genes for benign familial infantile seizures on a novel locus." in: The International journal of neuroscience, Vol. 120, Issue 3, pp. 217-21, 2010 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

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