Lin-28 Homolog A (C. Elegans) (LIN28A) antibody

Details for Product No. ABIN387790
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Antigen
Synonyms Lin28, csdd1, lin-28, lin28, zcchc1, LIN28, CSDD1, LIN-28, ZCCHC1, lin-28A, AL024421, ENSMUSG00000070700, Gm10299, Lin-28, Tex17, RGD1566408, sb:cb650, zgc:55584
Reactivity
Human
(81), (30), (21), (13), (13), (1)
Host
Mouse
(59), (25)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
(66), (40), (22), (21), (17), (14), (10), (9), (9), (4), (3)
Pubmed 5 references available
Quantity 400 µL
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Catalog No. ABIN387790
291.50 $
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Immunogen LIN28A recombinant protein is used to produce this monoclonal antibody.
Clone 55CT58-12-1
Isotype IgG1 kappa
Specificity LIN28A recombinant protein is used to produce this monoclonal antibody.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name LIN28A
Background Synonyms: Lin-28 homolog A, Zinc finger CCHC domain-containing protein 1, LIN28, CSDD1, LIN28A, ZCCHC1
Molecular Weight 22743 Da
Gene ID 79727
UniProt Q9H9Z2
Research Area Translation Factors, Stem Cells, Signaling
Application Notes WB = 1:200-2000, IHC = 1:50-200, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Lin-28 Homolog A (C. Elegans) (LIN28A) antibody Western blot analysis of LIN28 recombinant protein by anti-LIN28A Monoclonal Antibody (ABIN387790). LIN28 (arrow) was detected using the purified Mab. Formalin-fixed and paraffin-embedded human testis tissue reacted with LIN28A Monoclonal Antibody (ABIN387790), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
anti-Lin-28 Homolog A (C. Elegans) (LIN28A) antibody (2) anti-Lin-28 Homolog A (C. Elegans) (LIN28A) antibody (Image 2)
Background publications West, Viswanathan, Yabuuchi et al.: "A role for Lin28 in primordial germ-cell development and germ-cell malignancy." in: Nature, Vol. 460, Issue 7257, pp. 909-13, 2009 (PubMed).

Heo, Joo, Kim et al.: "TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation." in: Cell, Vol. 138, Issue 4, pp. 696-708, 2009 (PubMed).

Iliopoulos, Hirsch, Struhl: "An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation." in: Cell, Vol. 139, Issue 4, pp. 693-706, 2009 (PubMed).

Qiu, Ma, Wang et al.: "Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells." in: Nucleic acids research, Vol. 38, Issue 4, pp. 1240-8, 2010 (PubMed).

Peng, Maihle, Huang: "Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer." in: Oncogene, Vol. 29, Issue 14, pp. 2153-9, 2010 (PubMed).

Validation Images
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