ATG12 antibody

Catalog No. ABIN387794

The Mouse Monoclonal anti-ATG12 antibody has been validated for WB. It is suitable to detect ATG12 in samples from Human. There is 1 publication available.

Quick Overview for ATG12 antibody (ABIN387794)

Target: ATG12 (Autophagy Related 12 (ATG12))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ATG12 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 43CT73-3-5-5-4

Product Details anti-ATG12 Antibody

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: APG12L recombinant protein is used to produce this monoclonal antibody.

Isotype: Ig kappa, IgG2b

Application Details

Application Notes: WB: 1:4000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-ATG12 antibody (ABIN387794)

Sanchez, Penfornis, Oskowitz, Boonjindasup, Cai, Dhule, Rowan, Kelekar, Krause, Pochampally: "Activation of autophagy in mesenchymal stem cells provides tumor stromal support." in: Carcinogenesis, Vol. 32, Issue 7, pp. 964-72, (2011) (PubMed).

Target Details for ATG12

Target: ATG12 (Autophagy Related 12 (ATG12))

Alternative Name: ATG12

Background: Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).

Molecular Weight: 15113

Gene ID: 9140

NCBI Accession: NP_001264712, NP_004698

UniProt: O94817

Pathways: Autophagy