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Lysine (K)-Specific Demethylase 4A (KDM4A) (N-Term) antibody

Antigen

Lysine (K)-Specific Demethylase 4A (KDM4A)
Synonyms JMJD2, JHDM3A, JMJD2A, KIAA0677, Jmjd2, Jmjd2a, MGC28562, mKIAA0677, D4Ertd222e, DKFZp469L1915
Binding Site
Alternatives

N-Term
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
1 reference available
Certificates ISO 9001:2008
Catalog no. ABIN387900
Quantity 400 µL  (0.25 mg/ml)
Price 280.50 $   Plus shipping costs $45.00
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anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (N-Term) antibody

Additional Information
Application Details Publications Images Alternatives back to top

Alternative name JMJD2A
Gene ID 9682
UniProt NP_055478
Immunogen This JMJD2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 536~565 amino acids from the N-terminal region of human JMJD2A.
Isotype Ig
Description Other names: JMJD2A, JHDM3A, JMJD2, KIAA0677
Characteristics Purified Rabbit Polyclonal Antibody (Pab)
Specificity This JMJD2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 536~565 amino acids from the N-terminal region of human JMJD2A.
Molecular Weight 120720 DA
Comments

Background: JMJD2A is a member of the Jumonji domain 2 (JMJD2) family and a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.

Application Details
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Application Notes The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:50~100
Concentration 0.25 mg/ml
Purification Purified
Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles
Research Area Signaling, Protein Modifications, Cell Cycle, Transcription Factors, Cell Structure
Restrictions For Research Use only

Publications
Application Details Images Alternatives back to top

Product Gray, Iglesias, Lizcano et al.: "Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein." in: The Journal of biological chemistry, Vol. 280, Issue 31, pp. 28507-18, 2005 (PubMed).

Alternatives
Application Details Publications Images back to top

Alternatives for antigen "Lysine (K)-Specific Demethylase 4A (KDM4A)", type "Antibodies"
Hosts Rabbit (24), Mouse (7), Sheep (1)
Reactivities Human (30), Mouse (Murine) (20), Rat (Rattus) (20)
Applications Immunofluorescence (IF) (16), Western Blotting (WB) (12), ELISA (11), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Immunohistochemistry (IHC) (5), Dot Blot (Dot) (2), Immunocytochemistry (ICC) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunostaining (ISt) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes Internal Region (1), Middle Region (1), N-Term (1), pTyr547 (1)