K(lysine) Acetyltransferase 5 (KAT5) (N-Term) antibody

Antigen: K(lysine) Acetyltransferase 5 (KAT5)

Synonyms: PLIP, 60kDa, Tip55, Tip60, Htatip, Htatip1, AI839539, MGC117972, MGC95167, TIP, ESA1, TIP60, cPLA2, HTATIP, HTATIP1, 6121, CG6121, DmEG0007.7, Dmel/TIP60, DmelCG6121, DmelTIP60, dmHAG405, dTip60, dTIP60, EG0007.7, EG:EG0007.7

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN387933

Additional Information

Alternative name: KAT5 / Tip60/HTATIP

Gene ID: 10524

UniProt: Q92993

Immunogen: This KAT5 / Tip60/HTATIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41~71 amino acids from the N-terminal region of human HTATIP.

Isotype: Ig

Description: Other names: 60 kDa Tat interactive protein, Tip60, HIV-1 Tat interactive protein, cPLA(2) interacting protein,

Characteristics: Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This KAT5 / Tip60/HTATIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41~71 amino acids from the N-terminal region of human HTATIP.

Molecular Weight: 58582 DA

Comments:

Background: HTATIP belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction.

Synonyms: PLIP, 60kDa, Tip55, Tip60, Htatip, Htatip1, AI839539, MGC117972, MGC95167, TIP, ESA1, TIP60, cPLA2, HTATIP, HTATIP1, 6121, CG6121, DmEG0007.7, Dmel/TIP60, DmelCG6121, DmelTIP60, dmHAG405, dTip60, dTIP60, EG0007.7, EG:EG0007.7

Application Details

Application Notes: The suggested dilution is: ELISA~~1:1,000 Western blotting~~1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Signaling, Cell Signaling, Protein Modifications, Cancer, Transcription Factors, Chromatin, Cell Structure

Restrictions: For Research Use only

Images

Western blot analysis of anti-HTATIP Pab (ABIN387933) in Jurkat cell line lysates (35ug/lane). HTATIP(arrow) was detected using the purified Pab.

Western blot analysis of anti-HTATIP Pab(ABIN387933) in mouse liver tissue lysate (35ug/lane). HTATIP(arrow) was detected using the purified Pab.

Publications

Product: Cai, Jin, Florens et al.: "The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes." in: The Journal of biological chemistry, Vol. 280, Issue 14, pp. 13665-70, 2005 (PubMed).