|+1 404 474 4654|
|+1 888 205 9894 (TF)|
APOBEC3B (PHO3) (C-Term) antibody
Western Blotting (WB), ELISA
|2 references available|
|Quantity||400 µL (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This PHO3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307~337 amino acids from the C-terminal region of human PHO3.|
|Characteristics||Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This PHO3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307~337 amino acids from the C-terminal region of human PHO3.|
|Molecular Weight||28173 DA|
Background: PHO3 is a member of the cytidine deaminase gene family. The PHO3 gene is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control.
|Application Notes||The suggested dilution is: ELISA~~1:1,000 Western blotting: 1:50~100|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Cell Cycle, Signaling, Chromatin, Cell Structure|
|Restrictions||For Research Use only|
|Western blot analysis of hPHO3-D314 (ABIN388145) in mouse testis tissue lysates (35ug/lane). PHO3 (arrow) was detected using the purified Pab.|
Jarmuz, Chester, Bayliss et al.: "An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22." in: Genomics, Vol. 79, Issue 3, pp. 285-96, 2002 (PubMed).
Wedekind, Dance, Sowden et al.: "Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business." in: Trends in genetics : TIG, Vol. 19, Issue 4, pp. 207-16, 2003 (PubMed).