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Claudin 2 (CLDN2) (pTyr224) antibody

Details for Product No. ABIN390022
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Antigen
Synonyms CLDN2, zgc:92260, AL022813, RGD1560247
Epitope
pTyr224
(35), (14), (8), (8), (6), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Reactivity
Human
(83), (28), (13), (13), (1), (1), (1)
Host
Rabbit
(84), (4)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(6), (6), (6), (5), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Dot Blot (DB)
(67), (48), (35), (16), (15), (10), (8), (3)
Pubmed 2 references available
Quantity 400 µL
Options
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Catalog No. ABIN390022
291.50 $
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Immunogen This CLDN2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y224 of human CLDN2.
Clone RB16647
Isotype Ig
Specificity This Phospho-CLDN2-pY224 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 201~230 amino acids surrounding Y224 of human CLDN2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CLDN2
Background Members of the claudin protein family, such as CLDN2, are expressed in an organ-specific manner and regulate the tissue-specific physiologic properties of tight junctions.
Synonyms: claudin 2, SP82, CLD2
Molecular Weight 24418 DA
Gene ID 9075
UniProt NP_065117
Research Area Phospho-specific antibodies, Cell Structure
Application Notes DB = 1:500
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Claudin 2 (CLDN2) (pTyr224) antibody Dot blot analysis of anti-Phospho-CLDN2-pY224 Antibody (ABIN390022) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/mL.
Background publications Furuse, Fujita, Hiiragi et al.: "Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin." in: The Journal of cell biology, Vol. 141, Issue 7, pp. 1539-50, 1998 (PubMed).

Morita, Furuse, Fujimoto et al.: "Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 2, pp. 511-6, 1999 (PubMed).

Validation Images
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