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Details for Product No. ABIN390022

Claudin 2 (CLDN2) (pTyr224) antibody

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Antigen
Synonyms AL022813, RGD1560247, CLDN2, zgc:92260
Epitope
»Alternatives pTyr224
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Dot Blot (DB)
Pubmed 2 references available
Catalog no. ABIN390022
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This CLDN2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y224 of human CLDN2.
Clone RB16647
Isotype Ig
Specificity This Phospho-CLDN2-pY224 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 201~230 amino acids surrounding Y224 of human CLDN2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CLDN2
Background Members of the claudin protein family, such as CLDN2, are expressed in an organ-specific manner and regulate the tissue-specific physiologic properties of tight junctions.
Synonyms: claudin 2, SP82, CLD2
Molecular Weight 24418 DA
Gene ID 9075
UniProt NP_065117
Research Area Phospho-specific antibodies, Cell Structure
Application Notes Recommend dilutions: DB : 1:500
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Furuse, Fujita, Hiiragi et al.: "Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin." in: The Journal of cell biology, Vol. 141, Issue 7, pp. 1539-50, 1998 (PubMed).

Morita, Furuse, Fujimoto et al.: "Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 2, pp. 511-6, 1999 (PubMed).

Alternatives for antigen "Claudin 2 (CLDN2)", type "Antibodies"
Hosts (56), (4)
Reactivities (53), (26), (14), (13), (1), (1), (1)
Applications (41), (21), (19), (17), (10), (6), (3), (3), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (20), (8), (2), (2), (2), (2), (2), (2), (2), (2), (1)
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