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Claudin 2 (CLDN2) (pTyr224) antibody

Details for Product No. ABIN390022, Supplier: Login to see
Antigen
  • CLDN2
  • zgc:92260
  • AL022813
  • RGD1560247
Epitope
pTyr224
66
27
16
13
10
9
9
7
5
3
3
3
2
2
2
1
1
1
1
Reactivity
Human
151
34
25
5
4
4
2
Host
Rabbit
151
7
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
11
11
10
10
10
8
1
1
1
1
1
1
1
1
1
Application
Dot Blot (DB)
113
92
65
32
23
16
11
8
5
2
1
Supplier
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Immunogen This CLDN2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y224 of human CLDN2.
Clone RB16647
Isotype Ig
Specificity This Phospho-CLDN2-pY224 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 201~230 amino acids surrounding Y224 of human CLDN2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CLDN2 (CLDN2 Antibody Abstract)
Background Members of the claudin protein family, such as CLDN2, are expressed in an organ-specific manner and regulate the tissue-specific physiologic properties of tight junctions.
Synonyms: claudin 2, SP82, CLD2
Molecular Weight 24418 DA
Gene ID 9075
NCBI Accession NP_065117
Research Area Phospho-specific antibodies, Cell Structure
Pathways
Application Notes DB = 1:500
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Dot Blot (DB) image for anti-Claudin 2 (CLDN2) (pTyr224) antibody (ABIN390022) Dot blot analysis of anti-Phospho-CLDN2-pY224 Antibody (ABIN390022) on nitrocellulose...
Background publications Morita, Furuse, Fujimoto et al.: "Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 2, pp. 511-6, 1999 (PubMed).

Furuse, Fujita, Hiiragi et al.: "Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin." in: The Journal of cell biology, Vol. 141, Issue 7, pp. 1539-50, 1998 (PubMed).