BUD31 antibody (N-Term)
Quick Overview for BUD31 antibody (N-Term) (ABIN390083)
Target
See all BUD31 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 21-50, N-Term
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Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogen
- This EDG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human EDG2.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Expiry Date
- 6 months
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: "The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 25, pp. 9643-8, (2006) (PubMed).
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- BUD31 (BUD31 Homolog (BUD31))
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Alternative Name
- EDG2
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Background
- The EDG2 integral membrane protein is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion.
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Molecular Weight
- 41109
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Gene ID
- 1902
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NCBI Accession
- NP_001392, NP_476500
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UniProt
- Q92633
Target
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