You are viewing an incomplete version of our website. Please click to reload the website as full version.

Granzyme B (GZMB) (AA 2-32), (N-Term) antibody

Details for Product No. ABIN390495, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

AA 2-32, N-Term
(40), (14), (13), (12), (12), (12), (7), (6), (6), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Human, Mouse (Murine)
(230), (65), (34), (11), (5), (4), (1)
(128), (107), (19)
Clonality (Clone)
Polyclonal ()
(17), (16), (8), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(127), (69), (63), (62), (53), (30), (22), (17), (14), (10), (8), (4), (4), (3), (2), (2), (1), (1), (1), (1), (1)
Pubmed 3 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 400 μL
Shipping to United States ( )
Availability Will be delivered in 2 to 4 Business Days
Immunogen This GZMB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-32 AA from the N-terminal region of human GZMB.
Clone RB19352
Isotype Ig
Specificity This GZMB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10~39 amino acids from the N-terminal region of human GZMB.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name GZMB
Background Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.
Synonyms: Granzyme B, Granzyme-2, T-cell serine protease 1-3E, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, SECT, Cathepsin G-like 1, CTSGL1, CTLA-1, Fragmentin-2, Human lymphocyte protein, HLP, C11, GRB, CTLA1, CSPB, CGL1, GZMB
Molecular Weight 27688 DA
Gene ID 3002
UniProt P10144
Research Area Apoptosis/Necrosis
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Granzyme B (GZMB) (AA 2-32), (N-Term) antibody (ABIN390495) Western blot analysis of GZMB antibody (N-term) (ABIN390495) in mouse stomach lysates...
Immunohistochemistry (IHC) image for anti-Granzyme B (GZMB) (AA 2-32), (N-Term) antibody (ABIN390495) GZMB Antibody (N-term) (ABIN390495) IHC analysis in formalin fixed and paraffin embed...
Flow Cytometry (FACS) image for anti-Granzyme B (GZMB) (AA 2-32), (N-Term) antibody (ABIN390495) GZMB Antibody (N-term) (ABIN390495) flow cytometric analysis of HL-60 cells (right hi...
Background publications Hagn, Schwesinger, Ebel et al.: "Human B cells secrete granzyme B when recognizing viral antigens in the context of the acute phase cytokine IL-21." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 3, pp. 1838-45, 2009 (PubMed).

Girnita, Webber, Brooks et al.: "Genotypic variation and phenotypic characterization of granzyme B gene polymorphisms." in: Transplantation, Vol. 87, Issue 12, pp. 1801-6, 2009 (PubMed).

Gaafar, Aljurf, Al-Sulaiman et al.: "Defective gammadelta T-cell function and granzyme B gene polymorphism in a cohort of newly diagnosed breast cancer patients." in: Experimental hematology, Vol. 37, Issue 7, pp. 838-48, 2009 (PubMed).

Catalog No. ABIN390495
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)