beta-Site APP-Cleaving Enzyme 1 (BACE) (N-Term) antibody

Antigen: beta-Site APP-Cleaving Enzyme 1 (BACE)

Synonyms: ASP2, BACE, HSPC104, FLJ90568, KIAA1149, C76936, Bace, bace1, MGC77409, BACE1, MGC137940, MGC145931, Bace1, ASP1, BAE2, DRAP, AEPLC, ALP56, ASP21, CDA13, CEAP1, ARP1, AI850424, 1110059C24Rik, bace2, MGC68881, MGC68482, BACE2

Epitope: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN392201

Additional Information

Characteristics: Purified Rabbit Polyclonal Antibody (Pab)

Alternative name: BACE1 (N-term)

Gene ID: 23621

Swiss-Prot: P56817

Immunogen: This BACE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47~76 amino acids from the N-terminal region of human BACE1.

Isotype: Ig  (Matching secondary antibodies)

Description: Other names: Beta-secretase 1 [Precursor], Beta-site APP cleaving enzyme 1, Beta-site amyloid precursor protein cleaving enzyme 1, Aspartyl protease 2, Asp 2, ASP2, Membrane-associated aspartic protease 2, Memapsin-2, BACE1, BACE

Specificity: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human BACE1.

Molecular Weight: 55764 DA

Synonyms: ASP2, BACE, HSPC104, FLJ90568, KIAA1149, C76936, Bace, bace1, MGC77409, BACE1, MGC137940, MGC145931, Bace1, ASP1, BAE2, DRAP, AEPLC, ALP56, ASP21, CDA13, CEAP1, ARP1, AI850424, 1110059C24Rik, bace2, MGC68881, MGC68482, BACE2

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:50~100 Immunohistochemistry~~ 1:10~50

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Neurology, Cell Structure

Restrictions: For Research Use only

Images

Western blot analysis of anti-BACE1 Antibody (N-term) (ABIN392201) in mouse heart tissue lysates (35ug/lane). BACE1(arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human brain tissue reacted with BACE1 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. clinical relevance has not been evaluated.