Transforming Growth Factor beta Receptor I (TGFBR1) (Center) antibody

Antigen: Transforming Growth Factor beta Receptor I (TGFBR1)

Synonyms: AAT5, ALK5, SKR4, ALK-5, LDS1A, LDS2A, TGFR-1, ACVRLK4

Epitope: Center

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN392279

Additional Information

Characteristics: Purified Rabbit Polyclonal Antibody (Pab)

Alternative name: TGF beta Receptor I (TGFBR1) (Center)

Gene ID: 7046

Swiss-Prot: P36897

Immunogen: This TGFBR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141~170 amino acids from the central region of human TGFBR1.

Isotype: Ig  (Matching secondary antibodies)

Description: Other names: TGF-beta receptor type I, TGFR-1, TGF-beta type I receptor, Serine/threonine-protein kinase receptor R4, SKR4, Activin receptor-like kinase 5, ALK-5

Specificity: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the central region of human TGFBR1.

Molecular Weight: 55959 DA

Application Details

Application Notes: The suggested dilution is: ELISA~~1:1,000 Western blotting~~1:100~500 Immunohistochemistry~~1:50~100

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure

Restrictions: For Research Use only

Images

Western blot analysis of anti-TGFBR1 Pab (ABIN392279) in Jurkat cell line lysates (35ug/lane). TGFBR1 (arrow) was detected using the purified Pab.

The anti-TGFBR1 Pab (ABIN392279) is used in Western blot to detect TGFBR1 in mouse small intestine tissue lysate.

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry. clinical relevance has not been evaluated. BC = breast carcinoma. HC = hepatocarcinoma.