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|+1 404 474 4654|
|+1 888 205 9894 (TF)|
seryl-tRNA Synthetase 2, Mitochondrial (SARS2) (Center) antibody
Alternatives Western Blotting (WB), Immunohistochemistry (IHC), ELISA
|3 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This SARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322~352 amino acids from the center region of human SARS2.|
|Description||Other names: Seryl-tRNA synthetase, mitochondrial [Precursor], EC 184.108.40.206, Seryl-tRNA(Ser/Sec) synthetase, Serine--tRNA ligase, SerRSmt, SARS2, SARSM|
|Characteristics||Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This SARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322~352 amino acids from the center region of human SARS2.|
|Molecular Weight||58283 DA|
Background: SARS2 catalyzes the attachment of serine to tRNA(Ser). It is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Western blot~~1:50~100 Immunohistochemistry ~~ 1:10~50|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Metabolism, Cell Structure|
|Restrictions||For Research Use only|
Yokogawa, Shimada, Takeuchi et al.: "Characterization and tRNA recognition of mammalian mitochondrial seryl-tRNA synthetase." in: The Journal of biological chemistry, Vol. 275, Issue 26, pp. 19913-20, 2000 (PubMed).
Gibbons, Yan, Li et al.: "Genomic organization, expression, and subcellular localization of mouse mitochondrial seryl-tRNA synthetase." in: Biochemical and biophysical research communications, Vol. 317, Issue 3, pp. 774-8, 2004 (PubMed).
Müller, Deschauer, Neudecker et al.: "Late-onset mitochondrial myopathy with dystrophic changes due to a G7497A mutation in the mitochondrial tRNA(Ser(UCN)) gene." in: Acta neuropathologica, Vol. 110, Issue 4, pp. 426-30, 2005 (PubMed).
|Reactivities||Human (10), Mouse (Murine) (3), Rat (Rattus) (3)|
|Applications||Western Blotting (WB) (9), ELISA (8), Immunohistochemistry (IHC) (4), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2)|
|Epitopes||N-Term (4), Center (1), Internal Region,AA 322-352 (1), N-Term,AA 167-196 (1)|