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Details for Product No. ABIN392546

P70 S6Kbeta (C-Term), (AA 452-482) antibody

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»Alternatives C-Term, AA 452-482
»Alternatives Human
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN392546
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This p70 S6Kbeta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 452-482 AA from the C-terminal region of human p70 S6Kbeta.
Clone RB0891
Isotype Ig
Specificity This p70 S6Kbeta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 453~482 amino acids from the C-terminal region of human p70 S6Kbeta.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Background This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B. Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
Synonyms: Ribosomal protein S6 kinase beta 2, 70 kDa ribosomal protein S6 kinase 2, p70 ribosomal S6 kinase beta, S6 kinase-related kinase, Serine/threonine-protein kinase 14 beta, RPS6KB2, STK14B
Molecular Weight 53483 DA
Gene ID 6199
UniProt Q9UBS0
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Cell Cycle, Signaling, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Gout, Minami, Hara et al.: "Molecular cloning and characterization of a novel p70 S6 kinase, p70 S6 kinase beta containing a proline-rich region." in: The Journal of biological chemistry, Vol. 273, Issue 46, pp. 30061-4, 1998 (PubMed).

Saitoh, ten Dijke, Miyazono et al.: "Cloning and characterization of p70(S6K beta) defines a novel family of p70 S6 kinases." in: Biochemical and biophysical research communications, Vol. 253, Issue 2, pp. 470-6, 1999 (PubMed).

Lee-Fruman, Kuo, Lippincott et al.: "Characterization of S6K2, a novel kinase homologous to S6K1." in: Oncogene, Vol. 18, Issue 36, pp. 5108-14, 1999 (PubMed).

Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Alternatives for antigen "P70 S6Kbeta", type "Antibodies"
Hosts (1)
Reactivities (1)
Applications (1)
Epitopes (1), (1)