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RPS6KB2 Products

(Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 (RPS6KB2))

Categories

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. [provided by RefSeq, Jul 2008].

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Featured RPS6KB2 Categories

RPS6KB2 Antibodies

High quality antibodies with extensive validation data.

RPS6KB2 ELISA Kits

Reliable ELISA kits for a wide range of species.

RPS6KB2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RPS6KB2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application FACS, IHC, ELISA, WB
Validations
  • (5)
Cat. No. ABIN3032485
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, WB
Validations
  • (5)
Cat. No. ABIN3028986
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application IF, WB
Validations
  • (1)
  • (3)
Cat. No. ABIN948425
Quantity 50 μg
Datasheet Datasheet

Recommended RPS6KB2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380783
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN2685396
Quantity 1 kit
Datasheet Datasheet

Recommended RPS6KB2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3082776
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3120302
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318842
Quantity 2 μg
Datasheet Datasheet

Latest Publications for our RPS6KB2 products

Wang, Li, Du, Xu, Wang, Zhang, Xu, Zeng, Mao, Cao: "The Class I PI3K inhibitor S14161 induces autophagy in malignant blood cells by modulating the Beclin 1/Vps34 complex." in: Journal of pharmacological sciences, Vol. 134, Issue 4, pp. 197-202, (2018) (PubMed).

Warner, Bridge, Hewitson, Hodgkinson, Heyam, Massa, Haslam, Chatzifrangkeskou, Evans, Plevin, Sharp, Lagos: "S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells." in: Nucleic acids research, Vol. 44, Issue 20, pp. 9942-9955, (2016) (PubMed).

Hiyama, Kusakabe, Takeshita, Sugi, Kuniyoshi, Imai, Kano, Kiso: "Nutrient starvation affects expression of LC3 family at the feto-maternal interface during murine placentation." in: The Journal of veterinary medical science, Vol. 77, Issue 3, pp. 305-11, (2015) (PubMed).

Kroczynska, Mehrotra, Majchrzak-Kita, Arslan, Altman, Stein, McMahon, Kozlowski, Kahle, Eklund, Fish, Platanias: "Regulatory effects of SKAR in interferon ? signaling and its role in the generation of type I IFN responses." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 31, pp. 11377-82, (2014) (PubMed).

Nardella, Lunardi, Fedele, Clohessy, Alimonti, Kozma, Thomas, Loda, Pandolfi: "Differential expression of S6K2 dictates tissue-specific requirement for S6K1 in mediating aberrant mTORC1 signaling and tumorigenesis." in: Cancer research, Vol. 71, Issue 10, pp. 3669-75, (2011) (PubMed).

Sridharan, Basu: "S6 kinase 2 promotes breast cancer cell survival via Akt." in: Cancer research, Vol. 71, Issue 7, pp. 2590-9, (2011) (PubMed).

Liu, Mao, LaFortune, Alonso, Gallick, Fueyo, Yung: "Cell cycle-dependent nuclear export of phosphatase and tensin homologue tumor suppressor is regulated by the phosphoinositide-3-kinase signaling cascade." in: Cancer research, Vol. 67, Issue 22, pp. 11054-63, (2007) (PubMed).

Cruz, Hedden, Boyer, Kharas, Fruman, Lee-Fruman: "S6 kinase 2 potentiates interleukin-3-driven cell proliferation." in: Journal of leukocyte biology, Vol. 78, Issue 6, pp. 1378-85, (2005) (PubMed).

Shao, Evers, Sheng: "Roles of phosphatidylinositol 3'-kinase and mammalian target of rapamycin/p70 ribosomal protein S6 kinase in K-Ras-mediated transformation of intestinal epithelial cells." in: Cancer research, Vol. 64, Issue 1, pp. 229-35, (2004) (PubMed).

Lekmine, Sassano, Uddin, Smith, Majchrzak, Brachmann, Hay, Fish, Platanias: "Interferon-gamma engages the p70 S6 kinase to regulate phosphorylation of the 40S S6 ribosomal protein." in: Experimental cell research, Vol. 295, Issue 1, pp. 173-82, (2004) (PubMed).

Synonyms and alternative names related to RPS6KB2

ribosomal protein S6 kinase B2 (RPS6KB2), ribosomal protein S6 kinase B2 (Rps6kb2), ribosomal protein S6 kinase, polypeptide 2 (Rps6kb2), 70kDa, KLS, p70(S6K)-beta, P70-beta, P70-beta-1, P70-beta-2, p70S6Kb, S6K-beta2, S6K2, SRK, STK14B

Protein level used designations for RPS6KB2

  • 70 kDa ribosomal protein S6 kinase 2
  • P70S6K2
  • S6 kinase-related kinase
  • S6K-beta
  • S6K-beta-2
  • p70 S6 kinase beta
  • p70 S6K-beta
  • p70 S6KB
  • p70 ribosomal S6 kinase beta
  • p70-S6K 2
  • ribosomal protein S6 kinase beta-2
  • serine/threonine-protein kinase 14 beta
  • serine/threonine-protein kinase 14B
  • ribosomal protein S6 kinase, 70kDa, polypeptide 2
  • S6 kinase 2
  • ribosomal protein S6 kinase, 70kD, polypeptide 2
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