RAPSN antibody (N-Term)

Catalog No. ABIN401664

The Goat Polyclonal anti-RAPSN antibody (ABIN401664) specifically detects RAPSN in WB and EIA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for RAPSN antibody (N-Term) (ABIN401664)

Target: RAPSN (Receptor-Associated Protein of The Synapse (RAPSN))

Reactivity: Human, Mouse, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This RAPSN antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-RAPSN Antibody

Binding Specificity: N-Term

Specificity: This antibody reacts to RAPSN.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence YQSNQTEKALQVWTK-C, from the N-Terminus of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/128000. Western blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for RAPSN

Target: RAPSN (Receptor-Associated Protein of The Synapse (RAPSN))

Alternative Name: RAPSN / RNF205

Background: Nicotinic acetylcholine receptors (AChRs) are organized into high-density postsynaptic clusters at the motor endplate that are critical for efficient synaptic transmission. The organization of AChRs is carried out by the 43 kDa cytoplasmic protein rapsyn. Studies have indicated that mutations which impair the activity of rapsyn can lead to the formation of congenital myasthenic syndrome (CMS). CMS is characterized by poor development of the postsynaptic region.Synonyms: 43 kDa postsynaptic protein, 43 kDa receptor-associated protein of the synapse, Acetylcholine receptor-associated 43 kDa protein, RAPsyn, RING finger protein 205

Gene ID: 5913

NCBI Accession: NP_005046

UniProt: Q13702